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The subject of the service is the quantification and valuation of the human health impacts of chemicals, based on quality-adjusted life-years (QALYs) and disability-adjusted life-years (DALYs) (and related concepts). The human health impacts of interest are those relevant to the chemicals which have been subject to previous REACH Annex XVII restrictions/restriction dossiers, which are listed in REACH Annex XIV or are on the 'Candidate List', or which are expected to be subject to restriction or prioritisation in the near future. Many of these chemicals are likely to be associated with health impacts which have already been subject to measurement using QALYs and DALYs.

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